منابع مشابه
Microfluidic large-scale integration.
We developed high-density microfluidic chips that contain plumbing networks with thousands of micromechanical valves and hundreds of individually addressable chambers. These fluidic devices are analogous to electronic integrated circuits fabricated using large-scale integration. A key component of these networks is the fluidic multiplexor, which is a combinatorial array of binary valve patterns...
متن کاملA Large Scale Thermal Microfluidic Valve Platform
Microfluidics engages with the manipulation of small amounts of liquids inside of technical systems. Often microfluidic structures need a high number of microfluidic valves to create complex systems for different applications. We suggest a phase change valve system and show its scalability to an array of 12 49 = 588 valves.
متن کاملSystem-Level Modeling and Synthesis Techniques for Flow-Based Microfluidic Very Large Scale Integration Biochips
Microfluidic biochips integrate different biochemical analysis functionalities on-chip and offer several advantages over the conventional biochemical laboratories. In this thesis, we focus on the flow-based biochips. The basic building block of such a chip is a valve which can be fabricated at very high densities, e.g., 1 million valves per cm 2. By combining these valves, more complex units su...
متن کاملLarge-Scale Integration of All-Glass Valves on a Microfluidic Device
In this study, we developed a method for fabricating a microfluidic device with integrated large-scale all-glass valves and constructed an actuator system to control each of the valves on the device. Such a microfluidic device has advantages that allow its use in various fields, including physical, chemical, and biochemical analyses and syntheses. However, it is inefficient and difficult to int...
متن کاملMicrofluidic large-scale integration: the evolution of design rules for biological automation.
Microfluidic large-scale integration (mLSI) refers to the development of microfluidic chips with thousands of integrated micromechanical valves and control components. This technology is utilized in many areas of biology and chemistry and is a candidate to replace today's conventional automation paradigm, which consists of fluid-handling robots. We review the basic development of mLSI and then ...
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ژورنال
عنوان ژورنال: Science
سال: 2002
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.1076996